Clarification of API and Chemical Slurries - Sponsored Whitepaper

Thin-Cake Filtration Technologies for Removing Activated Carbon, Catalysts and Other Trace Solids From Active Pharmaceutical Ingredient (API) Slurries

The BHS technologies of Vertical Candle Filters and Horizontal Pressure Plate Filters provide improved product quality with more efficient operations compared with manual pressure filters. The different technologies allow for the selection of the optimum process solution depending upon the cake characteristics and cake structure. Fully automatic operations provide for complete containment of the solids and liquids for reduced maintenance costs and overall project savings.

By Barry A. Perlmutter President and Managing Director

9123-115 Monroe Road Page 1 of 14 Charlotte, North Carolina 28270 Tel: 704.845.1190; Fax: 704.845.1902

INTRODUCTION As the pharmaceutical industry has changed and grown since the mid-1980's, there are increasing concerns about the safe handling of active pharmaceutical ingredients (APIs). To meet lower exposure limits of unknown compounds and to have batch-to-batch integrity with less operator interaction, the industry's need for new technologies has expanded.