Quality Management

Quality Management Research Library

NIR Prediction of Solid Dosage Form Dissolution Profiles
FOSS NIRSystems, Inc.
Dissolution testing is used in solid dosage form manufacturing to determine the rate of dissolution of the active pharmaceutical ingredient (API) into solvents that simulate the digestive tract fluids. There are several dissolution testing apparatuses described in the US Pharmacopeia. The general design has six to nine temperature-controlled 900mL vessels that contain the buffered solvent and a ...
 
A Picture or a Thousand Words? Graphic-Based Robot Programming Simplifies Cell Engineering
ABB Ltd
Text-based robot programming for machine tending applications requires engineers to have a high level of robotics expertise. Alternative graphical-based programs require less skill but fall short in providing a clear graphical overview of the machine tending cell and robot movement logic. ABB is developing a solution to the problem with a fast and user-friendly graphical-based model for intuitive ...
 
Reducing Costs at a Drinking Water Plant through Monitoring of Total Organic Carbon (TOC) and Process Optimization
GE Analytical Instruments
As many municipalities strive to balance regula- tions set forth in the USEPA’s Safe Drinking Water Act, they are growing more concerned about how to reduce spending in their plant treatment processes. Today many drinking wa- ter plants, like the City of City of Englewood’s Allen Water Filter Plant Englewood in Colorado, are using total organic carbon (TOC) monitoring and process optimization to ...
 
In Situ Monitoring of Osmolality and pH using Near Infrared Spectroscopy
FOSS NIRSystems, Inc.
Osmolality and pH are important cell culture process parameters, key elements that are often examined and optimized to improve the productivity of cell-culture–based bioprocesses. Osmolality affects cell viability and growth by regulating the transport of water and nutrients through cell membranes and pH maintains the isotonicity of a culture. To monitor these parameters in cell culture, samples ...
 
Unexpected Payoff of Switching to Electronic Device History Record
Camstar
What is most surprising is that while the benefits of electronic device history records (eDHR) align exactly with goals eagerly sought by manufacturing executives, few of these executives are aware of all that they can gain by the switch from a manual system. As a result, only about seven percent of the industry’s manufacturers have moved to a true eDHR and are reaping the benefits. By switching ...
 

Quality Management Video

FOSS XDS MasterLab - Content Uniformity with NIR Spectroscopy FOSS NIRSystems, Inc. The FOSS XDS MasterLab™ offers pharmaceutical manufacturers a rapid, reliable test method covering the full array of solid dosage forms: layered, coated ...
 
Screwless Feeding Technology using Bulk Solids Pump Feeders K-Tron Process Group The new K-Tron Bulk Solids Pump (BSP) feeders have been specifically designed and engineered to provide gentle, precise feeding of free-flowing pellets, ...
 
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