Quality Management

Quality Management Research Library

NIR Prediction of Solid Dosage Form Dissolution Profiles
FOSS NIRSystems, Inc.
Dissolution testing is used in solid dosage form manufacturing to determine the rate of dissolution of the active pharmaceutical ingredient (API) into solvents that simulate the digestive tract fluids. There are several dissolution testing apparatuses described in the US Pharmacopeia. The general design has six to nine temperature-controlled 900mL vessels that contain the buffered solvent and a ...
 
New Wet Chemical Oxidation Process for Total Organic Carbon (TOC) Analysis
GE Analytical Instruments
Sample matrices are known to create analytical obstacles during routine Total Organic Carbon (TOC) analysis. Until now, interferences from sample matrices have caused calibration curve stability to be sacrificed. Some common aggressive matrices require frequent maintenance, and weekly, or even daily recalibration. By re-engineering the sample flow path and the oxidation technique, GE Analytical ...
 
A Picture or a Thousand Words? Graphic-Based Robot Programming Simplifies Cell Engineering
ABB Ltd
Text-based robot programming for machine tending applications requires engineers to have a high level of robotics expertise. Alternative graphical-based programs require less skill but fall short in providing a clear graphical overview of the machine tending cell and robot movement logic. ABB is developing a solution to the problem with a fast and user-friendly graphical-based model for intuitive ...
 
In Situ Monitoring of CHO Cell Culture Medium using Near Infrared Spectroscopy
FOSS NIRSystems, Inc.
Near-infrared (NIR) spectroscopy is an analytical technique based on absorption measured in the near-infrared region of the electromagnetic spectrum, between the visible and the mid infrared. The fundamental absorption bands of chemical functional groups occur in the mid infrared and are very strong, so dilutions and very small path lengths are usually required to bring such absorbency within the ...
 
Design for Manufacturability - Build Quality by Design
Camstar
Medical Device manufacturers are facing some of the most difficult challenges ever encountered by the industry. As competition intensifies, they must innovate and capitalize on new opportunities and expedite time to market. Additionally, they must manage risk, increase product quality and reduce costs. These objectives pose a significant challenge as innovation, by its very nature, induces ...
 

Quality Management Video

FOSS XDS MasterLab - Content Uniformity with NIR Spectroscopy FOSS NIRSystems, Inc. The FOSS XDS MasterLabâ„¢ offers pharmaceutical manufacturers a rapid, reliable test method covering the full array of solid dosage forms: layered, coated ...
 
Flexible Screw Conveyors Flexicon Corporation A Flexicon flexible screw conveyor consists of a spring steel or stainless steel, flexible screw enclosed in a flexible or rigid plastic tube, or a rigid ...
 
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